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      APPLICATIONS

      Nanoencapsulation

      Microfluidizer® Technology Provides a Competitive Edge

      Nanoencapsulation is nanoscale particles or droplets surrounded by a coating or wall. This encapsulation is used to enclose one or more active ingredient and is used in the pharmaceutical, nutraceutical/food and cosmetic industries.

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      YOUR CHALLENGES

      Uniform Particle Size

      Achieving high drug loading with hydrophilic and hydrophobic drugs with uniform particle size has proven to be quite difficult.

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      HOW WE CAN HELP

      High Encapsulation Rates

      The use of Microfluidics technology can achieve reproducible, scalable particle sizes with high encapsulation rates of hydrophilic and/or hydrophobic drugs.

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      OUR APPROACH

      Easy to Use and Scalable

      Microfluidizer® processors are designed to be simple to use, clean and maintain. Conforming to cGMP requirements is an option for select equipment.

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      OUR EXPERIENCE

      Effective Solutions

      Let us use our decades of application development and machine engineering experience to help drive your product to market as quickly as possible.

      TECHNIQUES

      Nanoencapsulation Techniques

      Nanoencapsulation techniques using nanoemulsions, liposomes and polymers are primarily used in the pharmaceutical, nutraceutical/food and cosmetic industries.


      Nanoencapsulation enables companies to achieve:

      • Time release of actives (e.g., small and large molecule drugs, pesticides/herbicides)
      • Targeted drug delivery
      • Odor/flavor masking (e.g., fish oil)
      • Protection (e.g., vitamins, DNA, tattoo ink, fish oil) 
      CONTACT US

      Helping You Achieve High Encapsulation Rates

      For uniform particle size reliable results and he ability to scale up, look no further than Microfluidics. Use the form to get in touch with our experts who will be happy to offer support and guidance.

      ADVANTAGES

      Benefits of Microfluidizer® Technology for Nanoencapsulation

      Customers using Microfluidizer® technology for nanoencapsulation applications enjoy competitive differentiation for their products and processes:

      • Smaller particle sizes
      • Uniform particle size distribution
      • Efficient encapsulation rates
      • Effective cooling
      • Precise shear
      • Controlled mixing intensity of reactant streams
      • Ease of use, cleaning and maintenance
      • Scaleup guaranteed
      RESULTS

      Proven Drug Nanoencapsulation Results

      Nanoemulsions

      Fish oil contains Omega-3 fatty acid, an essential nutrient. Encapsulating the fish oil using a nanoemulsion substantially reduces its undesirable taste and protects the oil from oxidation.

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      Polymers

      Microfluidizer® technology is ideally suited for applications requiring highly efficient polymer encapsulation.

      Polydispersity

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      Liposomes

      In the example below, 0.1% plasmid DNA is encapsulated inside a Palmitoyl oleoyl phophatidyl choline liposome. DNA remains.

      DNA Encapsulation in a Liposome

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      BLOG ARTICLES

      Expert Advice and Information

      Recommended downloads for manufacturers working in the pharmaceutical industry.

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      Nanoemulsion Production - Small Particles Producing a Big Result

      Feb 5, 2025 2:09:05 PM

      The potential applications of nanoemulsions are vast and varied. In..

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      Advancing Global Health at AAPS PharmSci 360 2024

      Oct 29, 2024 6:40:24 PM

      A team of experts in equipment and applications from Microfluidics participated..

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      Microfluidics is Awarded the Biotech Innovation Award at Interphex

      Apr 25, 2024 7:19:09 PM

      The Microfluidics team of experts was proud to exhibit at the 2024 Interphex..