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LM20 Microfluidizer® Processor

Electrically Powered High Shear Lab-Scale Unit 

The LM20 Microfluidizer® high-pressure processor ensures that 100% of your material undergoes exactly the same treatment, yielding consistently reliable results that include uniform particle and droplet size reduction, submicron emulsions and high-yield cell disruption.

Our unique design converts pressure into shear forces more efficiently than other technologies, delivering superior performance. The LM20’s unique intensifier pump supplies the desired pressure at a constant rate to your materials, driving them through precisely defined, fixed-geometry microchannels within the Interaction Chamber™. The product stream accelerates to high velocities, creating shear rates that are orders of magnitude greater than any other conventional method.

The LM20 Microfluidizer® benchtop homogenizer can easily and linearly be scaled up to larger volumes.  By operating under the same conditions, our LM20 Microfluidizer® processor can seamlessly achieve consistent, reliable results on the pilot and production models.


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LM20 Microfluidizer® Processor


Standard Features

  • 300 ml glass reservoir
  • Diamond Interaction Chamber™ (ceramic chamber is standard on LM20-20 model)
  • Digital pressure control
  • Integrated stroke counter with maintenance reminder
  • Multiple languages (selectable by user)

Optional Features

  • Auxiliary Processing Module™ (APM™)
  • Cooling coil, bath & recirculation assembly
  • Process pressure gauge
  • Larger capacity stainless steel reservoirs
  • Solvent-resistant gasket materials
  • Seal quench fittings
  • Nitrogen adapter assembly
LM20 Microfluidizer® Processor


Like all Microfluidizer® processors, the digitally controlled LM20 excels at efficiently converting high fluid pressures to intense shear forces.

  • Requires a minimum sample size of 14 ml.
  • Is suitable for laboratory and benchtop applications.
  • Achieves unmatched particle/droplet size reduction/disruption performance at lower process pressure.
  • Limits sample temperature rise during processing, ensuring minimal heat denaturation of sensitive materials.
  • Results in higher product yields after sterile filtration with tighter particle size distribution.
  • Saves on development time in pilot/production scale with linear volumetric scale-up.
  • Provides enhanced repeatability with easy-to-use digital pressure control.
  • Incorporates a compact design that fits in a fume hood.
  • Ensures dependable process performance over time with maintenance reminder and operator alerts.

Our Range of High-Pressure Lab,
Pilot and Production Processors

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LM20 Microfluidizer® Processor


Each Microfluidizer® benchtop homogenizer is equipped with our patented fixed-geometry Interaction Chamber™. This crucial feature is at the core of our technology and is uniquely engineered to maximize the shear forces generated as fluids are forced through the homogenizer under intense pressures.

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Microfluidizer® high shear fluid processors serve a variety of applications due to their ability to achieve repeatable and scalable results in the areas of particle size reduction and distribution, dispersion, cell disruption and liposomes, lipid nanoparticles and much more. 

Microfluidics processors serve many industries, applications and volumes. Deciding which processor will depend on your particular nanoparticle challenge and goal.

The Microfluidics' Customer Care Team stands ready to consult with you to determine the right homogenizer for your specific needs.