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A major challenge for manufacturers is to formulate Hemp oil and CBD oil in such a way as to make it usable in consumable products. This is because of the following:
The issue of low bioavailability has been overcome in the pharmaceutical industry by producing nanoemulsions or other nanoencapsulations such as liposomes. These nano-formulations have been demonstrated to:
The Microfluidizer® processor technology is the only technology that can create nano-sized emulsions or encapsulations (liposomes) that meet all of the above requirements.
The Microfluidizer® processor provides the highest uniform shear rates on the market by utilizing a fixed geometry Interaction ChamberTM and extremely high constant processing pressures. The Microfluidizer® technology is also guaranteed to scale up so that product processing and results are consistent from R&D development to manufacturing. In addition, cGMP compliant Microfluidizer® processors have a proven track record meeting FDA requirements for food and pharmaceutical production.
Molecular weight reduction of cannabis oil is common practice. This technique reduces the viscosity and makes the oil easier to work with in delivery methods such as vaporizers. Chemical processing modifies the chemical structure of cannabinoids and the chemicals add cost and undesirable contaminants, which increases the requirements for approval, testing and regulation. A Microfluidizer® processor is superior to a chemical approach because it does not require any chemicals in the process and will not alter the cannabinoids.
For producers, extractors, and processors who want improved CBD and cannabis related products, the Microfluidizer® high shear processors provide a scalable solution with the highest efficiency. The resulting unique formulations will differentiate your products with improved shelf life, stability, and effectiveness.
Microfluidics International Corporation is part of the IDEX Material Processing Technologies (IDEX MPT) group of companies delivering a range of processing technologies for market leading products. This includes: Fitzpatrick Hammer Milling for Hemp Processing, Quadro Engineering Milling Equipment and High Shear Mixing Equipment
Please note - Microfluidics information and literature is intended only for the use of its equipment in jurisdictions where such activities are legal.
REFERENCES AS MENTIONED IN TEXT ABOVE:
(1) Goodwin R., Gustafson R.A., Barnes A., Nebro W., Moolchan E.T. $ Huestis M.A.(2006) - ∆9-tetrahydrocannabinol, 11-hydroxy-∆9-tetrahydrocannabinol and 11-nor-9-carboxy-∆ 9-tetrahydrocannavinol in human plasma after controlled oral administration of cannabinoids. [Ther Drug Monit. 24(4): pp 545-51]
(2) Lemberger L.,Weiss J.L., Watanabe A.M., Galanter I.M., Wyatt R.J., & Cardon P.V.(1972) - Delta-9 tetrahydrocannabinol: temporal correlation of the psychologic effects and blood levels after various routes of administration [N Engl J of Med. 286(13): pp 685-88]