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      TAMARA Specifications & Resources

      A benchtop solution for lipid nanoparticle formulation

      This page comprises in-depth details about the TAMARA nanoparticle formulation system to help you make an informed decision about the next steps in your RNA-LNP research and development.

      Read on for more information about the TAMARA working principle, unboxing, standard protocols and specifications.

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      TAMARA Working Principle

      TAMARA is designed for straightforward use, enabling both new and experienced users to achieve reliable, high-quality results in minutes. Set up and run your nanoparticle formulation experiment in less than 2 minutes—even on your first use—by following three simple steps:

      1. Set your parameters
      2. Pipette your sample
      3. Start your run

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      Unboxing

      See how TAMARA operates and what your initial setup will involve—watch the unboxing video to get started.

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      User Manual

      Access the TAMARA user manual for step‑by‑step operating guidance, clear instructions, and recommended best practices.

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      Standard Protocols

      Get a clear overview of using TAMARA with our standard RNA–LNP formulation protocol, plus performance data for common lipids.

      TAMARA Specifications

      Discover the full potential of TAMARA — read the brochure for key information.

      View the Brochure
      Inlet Volumes Depends on reservoir size
      Achievable Volumes
      (accuracy & repeatability)      		 0.2 to 30 mL
      Accuracy and repeatability ensured on 0.5 to 5 mL range with the first chip run
      TFR
      (total flow rate)      		 0.8 to 15 mL/min
      Depends on input parameters (pressure, volume,...) to ensure best accuracy and repeatability
      FRR
      (flow rate ratio solvent:water)      		 1:1 to 1:10
      Liquid Compatibility Any aqueous solution & solvent compatible with the wetted materials (Topas/COC and PEEK).
      Optimal Initial Lipid Concentration 1 to 10 mg/mL
      Can accommodate initial lipid concentration up to 100 mg/mL
      Inlet Gas Pressure 8 to 10 bar (120 to 150 psi)
      Lower pressure inlet can be accommodated but would decrease maximum accessible Total Flow Rate and cleaning capabilities.
      Only use dry and non corrosive nor explosive gas.
      Operating Temperature 10°C to 40°C
      Humidity Range 0 to 80% relative humidity
      Dimensions
      (height x width x depth)      		 Synthesis module: 23 x 26 x 23 cm
      Controller: 31 x 34 x 36 cm
      Weight Synthesis module: 3.650 kg
      Controller: 5.050 kg
      Power Supply 110-220 V
      45W
      Frequency 47-63Hz
      Neutral System TT
      Level of Pollution 1
      Device Class IP20
      Overvoltage Category II
      Device Protection 3
      Special Atmosphere No
      Installation Altitude 0 - 2,000 m above zero level

       

      What Can TAMARA Do?

      Formulation


        Lipid nanoparticles (RNA-LNP)

        Liposomes, micelles, polyplexes

        Polymer & hybrid nanoparticles

        Peptides nanoparticles

      Payloads


        mRNA, saRNA, circRNA, siRNA

        CRISPR-Cas9

        ASOs & DNA

        Small molecules & peptides

      Applications


        Preventive and therapeutic vaccines

        Gene editing & rare disease

        Oncology

        Personalized medicine