Microfluidizer^® Technology for
Creating RNA Vaccine Delivery Systems

Next-generation RNA vaccines have been a key area of research since the early 2000s because they can be produced quickly without complex manufacturing steps, making them well suited to pandemic response. However, RNA alone cannot be used as a vaccine and therefore requires an effective delivery system, typically using viral vectors or non-viral nanoparticles as carriers.

Lipid-based nanoformulations, such as lipid nanoparticles (LNPs), cationic nanoemulsions (CNEs), and nanostructured lipid carriers (NLCs), are the most advanced systems and have shown great promise.

This application note explain the most suitable approach for large-scale manufacturing & responding to pandemic situations.

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