Microfluidizer^® Technology for
Scalable Production of Lipid Nanoparticles

Lipid Nanoparticles (LNPs) are promising non-viral delivery vehicles composed of a specific mixture of lipids, including cationic/ionizable lipids, and other excipients.

This technology has recently gained prominence through COVID-19 vaccines, where LNPs are used as critical delivery systems for nucleic acids, especially mRNA. Beyond vaccines, they can deliver therapies for infectious diseases, immuno-oncology, genetic disorders, and neurodegenerative conditions.

In this application note, we explore how Microfluidizer^® Technology plays a vital role in safely producing lipid nanoparticles.